Let Angelina cut off the BRCA gene in breast and ovary, which may also have a lot to do with you – S-www.ggg138.com

Let Angelina? BRCA gene Julie resection of breast and ovary, may have a great relationship with you – [Shanghai] health Sohu in November 11, 2016, October 29th, the first large multicenter Chinese ovarian cancer patients with the BRCA mutation of data held in Portugal Lisbon IGCS (International Association of gynecologic cancer) Biennial Conference on release, fill in our country blank in this field. Sponsored by the Shanghai Cancer Institute of gynecological tumor Specialized Committee, AstraZeneca and BGI Co BRCA ovarian cancer patients Chinese first multicenter mutation research data released "press conference, director of Tumour Hospital Affiliated to Fudan University, Department of Obstetrics and Gynecology Professor Wu Xiaohua in charge of the study pointed out:" the first multicenter BRCA ovarian cancer patients Chinese mutation published research data the first provides a reliable and representative China patients with BRCA mutation status of the data for the further development of the academia, provides a theoretical foundation and basis for the accurate treatment scheme, the establishment of BRCA detection Chinese consensus in ovarian cancer patients." Once the BRCA mutation will significantly increase the risk of ovarian cancer ovarian cancer is one of the most common malignant tumors in women, according to the National Cancer Center, China’s annual ovarian cancer number of new cases is about 52 thousand and 100 people, the number of deaths of about 22 thousand and 500 people, mortality in gynecological malignant tumor in the first place. The incidence of ovarian cancer is hidden, and the lack of effective screening and early diagnosis measures, about 70% of patients in the diagnosis of late, there is widespread spread and metastasis of the tumor, the survival rate of 5 years is only about 30-40%. The study found that there is a close relationship between BRCA mutation and ovarian cancer, BRCA1 and BRCA2 are tumor suppressor gene, plays an important role in the regulation of cell replication, DNA repair, cell normal growth, if a BRCA mutation, loss of tumor suppressor function, resulting in a large number of reproductive cancer cells. The study found that the risk of ovarian cancer for the general population is about 1%, and the risk of ovarian cancer in BRCA1 mutation carriers can be as high as 40%, BRCA2 mutation in ovarian cancer risk carriers can be increased to 11-18%. Therefore, BRCA detection can not only be an important reference data for the screening of high-risk individuals of ovarian cancer, but also has great clinical significance for the treatment of patients with ovarian cancer. Angelina, a famous American film star, has been tested for BRCA1 mutations to prevent the removal of bilateral ovaries and fallopian tubes to prevent ovarian cancer. For a time, BRCA testing has become a hot topic in society. 28.45% Chinese ovarian cancer patients with BRCA mutations in recent twenty years, many foreign literatures reported in patients with ovarian cancer BRCA mutations roughly in the ratio of 5-29%, but few data from Asia, especially in China, because the BRCA test is not a routine test, so it is not a large-scale, multi center study data. Department of oncology, Tumour Hospital Affiliated to Fudan University, Chinese Academy of Medical Sciences, Qilu Hospital, Zhongshan University, Shandong, china"相关的主题文章: